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THE Q & A

Welcome to The Q&A with Elaine Moore. Registered members are invited to ask any question of Elaine Moore on autoimmune diseases, Graves' disease, other thyroid diseases and subconditions, laboratory work, traditional and complementary medicine, triggers and environmental influences, thyroid and immune disorders in pets and animals, and other relevant areas of inquiry.

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Questions are answered solely by Elaine Moore, a medical writer and clinical laboratory scientist, MT, CLS, with more than 30 years of experience in immunology. Moore has also authored and edited over a dozen books in the area of health sciences and is an editor for McFarland Publisher's Health Topics Series.


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 2/28/2009 7:20 AM
 

Hi Elaine,

 
Had a blood test yesterday morning... I usually use the hospital lab because other labs aren’t as accurate and they use the old lab ranges, but they are no longer accepting out patients, so I had to go the regular lab.

*taken 8:40am, 21st day of cycle, 10 days after being on ldn, but 2 days after stopping it

sodium 141 (135 - 145)
potassium 4.0 (3.3 - 5)
TSH <0.01 (whoa, low)
FT4 9 (10 - 20)
FT3 5.5 (2.6 - 5.7) (hosp lab for this is 4 – 6.8)
cortisol 347 (170 - 540)
Anti TPO - NEGATIVE!!!
Anti Thyrog - NEGATIVE!!!
Thyrog <0.2 (<50 range)
Estrogen 336 (usually I am around 500ish at this time)
Progesterone 37.3 (4 – 50) This is low for me

Previous labs – about 4 weeks before using the hospital, so, note the current lab ranges for T3
 
TSH 0.01 (0.4 -3.8)
FT4 11 (12 - 21)
FT3 5.3 (4-6.8)
cortisol 410 (170-540) @ 9am
sodium 141 (135-145)
potass 4.3 (3.5-5)
Estrogen 886 (really high for me)
Progesterone 61

Ok, so this is my take ... my antibodies dropped (this lab just does 'negative' or 'positive' so i don't have numbers, but it used to be 400+  for anti-thyr and 110 for anti-tpo). So, antibodies dropped, everything got into the cells, and relatively, i went hyper?. But, as you can see, its hard on my adrenals because my blood cortisol levels, for the past 15 blood tests have been over 410 in the morning, if not 500. What’s your take on it Elaine? I guess I should lower the armour. Should I take adrenal supplements? Any recommendations?
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 3/1/2009 1:22 PM
 

Hi,

You show absolutely no signs of adrenal insufficiency and have probably been misinformed about adrenal exhaustion. In adrenal insufficiency cortisol levels are very low. Your cortisol level is higher than most people's that we see in the lab, and a high cortisol is not considered desirable. Higher cortisol levels are seen in people with chronic stress and other conditions. Most people with a cortisol level near the high end of the range would be asking about ways to reduce it. People in the medical profession generally strive for levels near 170.

Antibody-wise, TPO antibodies are markers of thyroid inflammation. Thyroid inflammation falls when there is adequate thyroid hormone and it increases in inflammatory thryoid disease. Thyroglobulin antibodies are seen in both Graves' disease and Hashimoto's thyroiditis but they're much higher in people with HT.

Your TSH is low because your FT3 level is high, most likely too high for your body's needs. Your FT4 is likely too low for your body's needs. Your dose of Armour isn't really working. Armour has a slightly higher ratio of T3 to T4 than humans make. For many people, especially those who have trouble converting T4 into T3, Armour works fine. For others, FT3 is too high relative to FT4.

Ideally, you'd be on a lower dose of T3 and a higher dose of T4.  Options would be to try levothyroxine alone using a higher dose like perhaps 0.15 mg levothyroxine. Then if your FT3 is below mid-range you'd add T3 (Cytomel) or you'd use 0.1 mg levothyroxine with only 1 grain (60 mg) Armour.

You want to rely on FT3 and FT4 to find an optimal dose of replacement hormone. TSH is frequently misleading on people on Armour, and if you have TSH receptor antibodies these antibodies falsely decrease TSH.  Stress reduction techniques would be a good step toward helping to reduce your cortisol levels. Best, Elaine

 

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