Hi Michelle,
Toxic multinodular goiter (TMG) s the second most common cause of hyperthyroidism. Here, the word toxic refers to the development of hyperthyroidism and not to toxicity. Multiple nodules are rarely malignant. If one nodule stood out and was much larger than the others your doctor would do a biopsy first, but this is rarely needed in cases of TMG.
PTU and methimazole are both used to reduce the size of thyroid nodules and the associated hyperthyroidism. A low iodine diet is also used in TMG and often that's all that's needed. There's no reason for aggressive therapy such as RAI. Your doctor should be running FT4 and FT3 levels and as soon as FT4 is within the normal range, the PTU dose should be reduced. You'll only need a low dose of meds to help lower the production of new hormone.
In the rare instance of thyroid cancer, and again, most nodules are benign, RAI isn't necessary.
Best, Elaine