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Wednesday, February 08, 2012

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Welcome to The Q&A with Elaine Moore. Registered members are invited to ask any question of Elaine Moore on autoimmune diseases, Graves' disease, other thyroid diseases and subconditions, laboratory work, traditional and complementary medicine, triggers and environmental influences, thyroid and immune disorders in pets and animals, and other relevant areas of inquiry.

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Questions are answered solely by Elaine Moore, a medical writer and clinical laboratory scientist, MT, CLS, with more than 30 years of experience in immunology. Moore has also authored and edited over a dozen books in the area of health sciences and is an editor for McFarland Publisher's Health Topics Series.

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Confused about Thyroid Peroxidase Antibodies

7/6/2010 10:12 AM

Deb

Joined: 3/27/2010

Posts: 3

Confused about Thyroid Peroxidase Antibodies

Hello Elaine,

I have Graves (in remission) and I wrote a few months ago regarding my TSH level going up, presumably due to the all of the soy I had been eating unaware. My doctor had said to come back in 3 months so here I am.

My TSH has gone down from 4.16 to 2.56, so that is looking better. My free thyroxine was also good (steady at 11). She did not test for free triiodothyronin. However, she did test for 'thyroid peroxidase A' (I think it got cut off on the test result paper they sent me) but she said she was going to test for antibodies? The result came back at 216 (the range being 0-35) but she said to come back in 6 months for another blood test. What does this mean? It seems very elevated to me. But I seem to be putting on weight, which is the opposite of Graves symptoms? I am so confused.

Any light you could shed on this would be greatly appreciated.

Many thanks,

Deb (:

7/7/2010 12:53 AM

Elaine

Joined: 8/1/2008

Posts: 3173

Re: Confused about Thyroid Peroxidase Antibodies

Hi Deb,

Thyroid peroxidase antibodies are markers of thyroid inflammation. They're usually much higher in Hashimoto's thyroiditis than in Graves' disease and can rise into the thousands. With your TSH improving you may have a better chance of keeping the weight off. I don't remember what treatment you're on, but if you're on ATDs your TSH is still probably too high. Be sure your FT4 is at least at mid-range and not at the low end of the range. You should be on the lowest dose of ATD (or the highest dose of replacement hormone if you're being treated for hypothyroidism) needed to keep FT4 at least at mid-range even if TSH is low. Best, Elaine

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