Update on previous post - Question and Answer Forum - Elaine Moore Graves' Disease and Autoimmune Disease Education

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Wednesday, February 08, 2012

..:: Q & A ::..

THE Q & A

Welcome to The Q&A with Elaine Moore. Registered members are invited to ask any question of Elaine Moore on autoimmune diseases, Graves' disease, other thyroid diseases and subconditions, laboratory work, traditional and complementary medicine, triggers and environmental influences, thyroid and immune disorders in pets and animals, and other relevant areas of inquiry.

Each thread represents one question with one answer and will only appear at the time it is answered. Once answered, further replies cannot be made to the same thread since each thread represents only one question. A new thread will need to be started for additional questions.

Questions are answered solely by Elaine Moore, a medical writer and clinical laboratory scientist, MT, CLS, with more than 30 years of experience in immunology. Moore has also authored and edited over a dozen books in the area of health sciences and is an editor for McFarland Publisher's Health Topics Series.

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Update on previous post

3/8/2010 1:44 PM

purelife

Joined: 2/11/2010

Posts: 22

Update on previous post

Dear Elaine,

“The rise in TSH even after a dose increase suggests your dose may still be too high. I can't remember if you were tested for thyroid antibodies but after miscarriage people can develop postpartum thyroiditis, a condition that causes a temporary (2 months or so) period of hyperthyroidism followed by a similar period of hyperthyroidism. What tests did you have to confirm your Graves' disease?”

With reference to your reply above, my dosage was reduced from 50mg to 25mg PTU, it was not increased. Usually TSH will rise after a dose reduction? My miscarriage happened at 6 weeks, which is very early loss. Will I develop postpartum thyroiditis?

My previous antibody result is TSI 135% and TPO 93 iu/ml

From Jane.

3/8/2010 4:27 PM

Elaine

Joined: 8/1/2008

Posts: 3174

Re: Update on previous postt

Hi Jane,

Sorry, that was a typo. I knew your dose had been decreased and with a decreased dose your thyroid levels should rise and you'd expect your TSH level to fall. Your TSH could have already been on the rise from before your dose was changed since you had symptoms of hypothyroidism. Or it could be rising if you're spontaneously moving into hypothyroidism. That's why I thought of postpartum thyroiditis (PPT).

PPT can occur after any pregnancy even if it's a very short duration. Your elevated TSI suggests you do have Graves' disease. However, Graves' that develops during pregnancy or during the postpartum period can run a course similar to that of PPT. For this reason, it's a good idea to watch for symptoms of hypothyroidism and ask to have your labs checked sooner if you notice any. Best, Elaine

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