Subclinical Hypothyroidism

By Elaine Moore

Subclinical hypothyroidism can cause many of the same symptoms as overt hypothyroidism, and it may increase your risk of heart problems.

Patients with subclinical hypothyroidism have slight elevations of TSH although their thyroid hormone levels are in the normal range. Recent studies indicate that patients with TSH levels >2.0 miu/L often show symptoms of subclinical hypothyroidism although TSH levels > 3.0 miu/L are generally used to diagnose subclinical hypothyroidism.

Patients with subclinical hypothyroidism along who also have positive thyroid antibody titers, either thyroglobulin, TPO, or TSH receptor antibodies, have a 5% risk annually of developing overt hypothyroidism.

Subclinical hypothyroidism can develop in Graves' patients who have been ablated even if they are on replacement therapy. Depending on the natural disease course, patients who have long been in remission after using ATD's can also suddenly develop subclinical hypothyroidism.

With the new AACE guidelines for TSH, more people than ever before will finally be diagnosed properly for both subclinical and overt hypothyroidism. According to the new guidelines the normal or reference range for TSH is now 0.3-3.0 mu/L. For patients on replacement hormone, the guidelines recommend keeping TSH within the range of 0.2-1.0 mu/L. ♦

© 21 May 2006 Copyrighted by Elaine Moore

Other Resources: 

Adding T3 Replacement Hormone for Mood Problems in Hypothyroidism


Elaine Moore Graves' Disease and Autoimmune Disease Education 
Copyrighted by Elaine Moore. © All Rights Reserved 
Last updated: Oct 24, 2015

The pages and their content, including all articles and images, are copyrighted and are not to be copied, reproduced or printed without written permission. This site is self-funded exclusively by Elaine Moore. Moore has no other external sources of funds and receives no monies from government agencies, pharmaceutical companies or other commercial entities to operate this site. There are no conflicts of interest in the operation of this site. Books by Elaine Moore are promoted in the Books section. This site complies with the HONcode standard for trustworthy health information. Disclaimer: The information at this site about the benefits or performance of any diagnostic or treatment is supported by scientific evidence such as medical journals, reports, articles, and other relevant materials. The educational information provided within is designed to help users better understand the nature of disease and the solutions available. Nothing contained on this website should be construed as or is intended to be used for medical diagnosis or treatment. It is recommended that a physician be consulted for diagnostic testing and treatment. Reference to any specific commercial or noncommercial products, services, processes, companies or trademarks does not constitute an endorsement or recommendation. Elaine Moore does not host any form of commercial advertisement or sponsor or endorse any products or services mentioned at the site, excluding her own copyrighted materials, articles, and books. The opinions, views, and recommendations of those registered to this site, are their own and do not represent those of Elaine Moore.